  
      "The Importance of Trace Minerals"
 
  Although most people know minerals are important to their
    health, few people know exactly why or even that much about them. Biochemically
    speaking. minerals are inorganic chemical elements not attached to a carbon
    atom.   
 
 
 
  There is a distinction between minerals and trace minerals
    (also called -trace elements) If the body requires more than 100 milligrams
    ( i.e., more than 1150th of a teaspoon) of 11 mineral each day. the substance
    is labeled a mineral. If the cellular body requires less than this, it
    is labeled a trace mineral.  
  Trace minerals are generally needed in quantities
    of only a few milligrams (mg) or micrograms (mcg) per day. For a list of the essential
    minerals and trace minerals as well as nonessential contaminants. please see Table 1 on NSN
    page 12. 
  When studying the relationship of minerals to human health,
    it becomes increasingly evident that keeping a balance level of minerals
    in every organ, tissue and cell of the human body may be a prominent key
    to maintaining a healthy existence. 
    As early as 1964, two mineral researchers wrote; "Even small departures from the 
    normal mineral composition of the milieu interior [the interior of the cell may 
    have profound physiological consequences...."
    Although minerals comprise only a fraction of total body weight, they are 
    crucial for many body functions including transporting oxygen, normalizing the 
    nervous system and simulating growth, maintenance and repair of tissues and 
    bones. 
  One can summarize the health benefits of some of the more
    important minerals and trace minerals as follow.  
  As stated below, these
    minerals and trace minerals can be of most benefit if they are in balance
    with other elements they interact with. 
  * Calcium: Essential for developing and maintaining healthy
    bones and teeth Assists in blood clotting. muscle contraction, nerve transmission,
    oxygen transport. cellular secretion of fluids and enzyme activity Optimal
    intake helps reduce risk of osteoporosis. 
  * Chromium: Aids in glucose metabolism and helps regulate
    blood sugar by potentiating insulin and serving as
    a component of glucose tolerance factor. 
  *
    Colbalt: Promotes the formulation of red blood
    cells and and serves as a component of the vitamin
    B-12. 
  * Copper: Essential to normal red blood cell 
    formation and connective tissue formation. Acts 
    as a catalyst to store and release iron to help form hemoglobin. Contributes to central nervous system function. 
  *
    lodine: Needed by the thyroid hormone to support
    metabolism. 
  * Iron: Necessary for red blood cell formation and
    Required for transport of oxygen throughout the 
    body. Important for brain function. Amount needed is
    higher in women of childbearing age. 
  * Magnesium: Activates over 100 enzymes and helps
    nerves and muscles function. Helps maintain the integrity
    of cell membranes and stabilizes the cell electrically
    Critical for proper heart function. 
  * Manganese: Key component of enzyme systems,
    including
    oxygen-handling enzymes Supports brain function and
    reproduction Required for blood sugar regulation Part of
    bone structure. 
  * Molybdenum: Contributes to normal growth and
    development Key component in many enzyme systems including
    enzymes involved in detoxification. 
  * Phosphorous: Works with calcium to develop and
    maintain strong bones and teeth. Enhances use of other nutrients Key role in cell membrane integrity and intercellular
    communication Critical for proper energy processing in the body 
  * Potassium: Regulates heartbeat, maintains fluid
    balance and helps muscles contract. 
  * Selenium: Essential component of a key antioxidant
    enzyme, necessary for normal growth and development Role in detoxification of heavy metals. such as mercury. Role
    in production of antibodies by the immune system.
    Component of teeth. 
  * Sulfur: Needed for structure of most protein, including
    muscles and hair. Critical role in liver detoxification. Important functions in antioxidant nutrients and oxygen
    handling Role in growth. 
  * Zinc: Essential part of more than 200 enzymes
    involved in digestion, metabolism, reproduction and wound healing Critical role in immune response Important
    antioxidant 
  
   
  There are even more benefits
    than these, so it is certainly easy to see that minerals play
    an important role in health. 
   
  Mineral Absorption   
   
   Every person absorbs minerals in a slightly different way--- a process called 
    biochemical individuality. According to Ruth L. Pike and Myrtle L. Brown in 
    their book Nutrition: Integrated Approach. “Whatever the nutritional potential 
    of a food, its contribution is nonexistent if it does not pass the test of 
    absorption. Those nutrients that have not been transferred through the 
    intestinal mucosal cell to enter the circulation have. for all nutritional 
    intent and purpose, never been eaten.  
   The variety of nutrients from the organism's environment that have been made 
    available by absorption must be transported through the circulatory system to 
    the aqueous microenvironment of the cells Then. they serve their ultimate 
    purpose -- participation in the metabolic activities in the cells on which the 
    life of the total organism depends.“’ 
   The absorption of minerals is dependent on many different factors. not the least 
    of which is age as well as adequacy of stomach acid output, balance of bowel 
    flora, presence or lack of intestinal illness”- and parasites, and amount of 
    dietary fiber intake.  
   Aging increases the risk of gastric atrophy, a condition that commonly is 
    associated with a decreased secretion of hydrochloric acid in the stomach. The 
    problem becomes that as a level of hydrochloric acid output decreases the body’s 
    ability to absorb minerals from the food-bound form diminishes. This inability 
    to adequately absorb minerals contributes to age-associated degeneration. Hence, 
    the form a mineral takes is crucial. since the less dependent It is on 
    hydrochloric acid to be absorbed, the more likely it will be able to be utilized 
    by the body.  
  Gastric atrophy or conditions such as achlorhydria (lack of stomach
    acid) or hypochlorhydria (inadequate stomach acid) can also impair the
    body’s absorption of important minerals. Achlorhydria has been found in
    children as young as five or six years of age. Hypochlorhydria, however, is more com-manly
    seen after age 35. It is estimated that between 15-35 percent of adults
    over age 60 have some degree of gastric atrophy, including hypochlorhydria.’ 
  Some acid-dependent minerals that require adequatestomach
    acid to enhance intraluminal absorption (the transferof nutrients to the
    circulatory system) in the small intestine include the following. 
   
            * chromium  
        * manganese  
        * copper  
        * molybdenum  
        * iron  
        * selenium  
        * magnesium
    and  
        * zinc  
     
   
  Nonessential Minerals / Contaminants 
   
  The absorption and efficient use of mineral in the body
    can also be affected by excessive levels of nonessential mineral contaminants
    such as aluminum, arsenic, cadmium, lead and mercury. These toxic minerals
    can have an “unbalancing” effect on the body’s cells (see Table 2). Cadmium,
    for example, an air pollutant from cigarette smoke and industrial emissions
    and a by-product of population growth, is experimentally known to cause
    hypertension, cancer and immune disorders. Cadmium acts like a classical
    stress agent. It has also been implicated in learning disabilities. Unlike
    lead, which has a short half-life in human tissue of from 30 to 100 days,
    cadmium has a half-life of between 10- 30 years.   
  While it is known
    that free cadmium is very toxic, it has also been found to greatly increase
    the toxicity of other agents. Cadmium has a unique capacity to form a close
    bond with chloride compounds such as the chlorinated pesticide lindane.
    When the two are combined, they alter liver metabolism and tissue levels
    of lindane double. Cadmium accumulates in cells that are the most malignant; in 
    prostate cancer, for example. there is a linear correlation between the grade of 
    malignancy and cadmium content. On the positive side, little cadmium is absorbed 
    orally unless there are nutrient deficiencies.  
   Recent research indicates that adequate dietary intake of essential minerals and 
    trace minerals may prevent and reduce affects of poisoning by environmental 
    pollutants and enhance the ability to work and learn. They can protect the body 
    from the effects of toxic minerals(4). Minerals that protect against cadmium and 
    other nonessential mineral contaminants are listed in Table 2. 
  Besides optimum levels and kinds of minerals to cope with
    toxicity, mineral requirements are affected by two other factors-- disease
    and drug-nutrient interaction Physical illness can raise demands for many
    trace elements. for example, the need for magnesium increases in heart
    disease and eating disorders.  
  And the demand for some minerals, such as
    zinc, increases under psychological, stress. Drug-nutrient interaction
    can also create deficiencies and imbalances of minerals at the cellular
    level For example, the absorption of iron from the gut can be reduced by
    antacids and tetracycline. Magnesium and zinc are hyper-excreted by those
    receiving oral diuretics, nephrotoxic drugs, penicillamine, or antacids
    containing aluminum  
    hydroxide. 
    
  Optimal Mineral Levels  
   
  Considering the importance of minerals to good health, establishing
    optimal mineral levels -- i.e. an update on the Recommended Dietary Allowances
    (RDAs), released in their 10th edition in 1989 -- is an urgent need. Recent
    analyses of data of nutrient and supplement intake in the United States
    conducted by the U.S. National Institutes of Health and other government
    agencies indicate that the vast majority of people in both affluent and
    emerging industrialized countries do not reach even 75 percent of the RDAs
    for 
    numerous trace minerals. 
  It is valuable to remember, however. that the realization
    of importance of trace minerals to human health is a recent discovery For
    example. only fifteen years ago, every textbook taught that the trace element
    boron was nonessential to all mammals, including man However, today, it
    is believed to be so important to human health that numerous scientists
    are preparing to petition the government to recognize boron as a trace mineral essential to human health. 
  Minerals and trace minerals do not exist by themselves
    but in relationships to one another Too much of one element can lead to
    imbalances in others, resulting in disease rather than the absence of disease.
    Factors such as diet, absorption ability, toxicities and drug-nutrient
    interactions play a role in maintaining a balance of trace elements in the body. 
   
  NSN REFERENCES (Table 1) Minerals, Trace Minerals And Mineral Contaminants 
   
  
    
      
        | Essential Minerals: | 
        Essential Trace and Minerals: | 
        Nonessential Contaminant Minerals: | 
       
      
        | Calcium | 
        Chromium+ | 
        Aluminum | 
       
      
        | Chloride* | 
        Copper+ | 
        Arsenic (in abundance) | 
       
      
        | Magnesium  | 
        Cobalt | 
        Barium | 
       
      
        | Phosphorus  | 
        Fluorine+ | 
        Beryllium  | 
       
      
        | Potassium* | 
        Iodine | 
        Cadmium | 
       
      
        | Sodium*  | 
        Iron | 
        Lead | 
       
      
        | Sulfur* | 
        Manganese | 
        Lithium | 
       
      
        |   | 
        Molybdenum | 
        Mercury  | 
       
      
        |   | 
        Selenium | 
        Rubidium | 
       
      
        |   | 
        Vanadium+ | 
        Strontium | 
       
      
        |   | 
        Zinc  | 
          | 
       
     
   
   
   l No RDAs set for these minerals Only estimated requirements
    are established for chloride, potassium and sodium No estimates  as yet established for sulfur.  
    + No RDAs as yet established for these minerals Estimated
    safe and adequate intakes are established for chromium, copper, chlorine, manganese and molybdenum There is no estimate as yet established
    for vanadium  
    NOTE: Several trace minerals that may be essential but
    have not yet been proven to be include minute amounts of arsenic, boron, nickel, silicon and tin.  
     
   
  (Table 2) Mineral Contaminants Guide  
   
  
    
      | Mineral  | 
      Contaminate Body Part Affected  | 
      Protective Nutrient | 
     
    
      | Aluminum  | 
      Stomach, bones, brain  | 
      Possibly magnesium None other known | 
     
    
      | Arsenic | 
      Cells (cellular metabolism)  | 
      Selenium, lodine, calcium, zinc, vitamin C, sulfur amino acids  | 
     
    
      | Cadmium | 
      Renal cortex of the kidney, heart, blood vessels
        to the brain appetite and smell center of the brain,
        every known process in the development of cancer  | 
      Zinc, calcium, vitamin C, sulfur ammo acids  | 
     
    
      | Lead | 
      Bones, liver, kidney, pancreas, heart, brain, nervous
        system  | 
      Zinc, iron, calcium, vitamin C, vitamin E, 
        sulfur amino acids  | 
     
    
      | Mercury | 
      Nervous system, appetite and pain centers of the
        brain, immune system, cell membranes  | 
      Selenium, vitamin C. pectin, sulfur amino 
        acids  | 
     
   
  (NFM 38) NFM’s Nutrition Science News l December 1995  
   
   
  
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